Radiogenomics workspace
Follow a gene, target or imaging concept across literature, open genomic frequency data, public imaging collections and trials, with every link labelled by how it was made.
- Radiogenomics relates imaging features, read by people or computed by software, to mutations, expression and other molecular features.
- Most published associations are retrospective and need external validation before they mean anything for care.
- RadioGx never infers an imaging-genomic association. Co-mentions in titles are shown as derived and “possible”.
- Paired imaging and genomic data are only claimed when a collection documents them.
How links are labelled on the evidence map
Source-reported
The record itself states the link, for example a trial listing an intervention. Drawn as a solid line.
Reference index
Curated RadioGx metadata such as a target’s gene or a radiopharmaceutical’s radionuclide. Verify at the official source.
Derived
RadioGx matched names or found terms together. Drawn dashed and never upgraded to “exact”.
Open a lens
Genes that come up often
Starting points drawn from the research literature. A gene appearing here says nothing about any person.
Public imaging collections
Well-known collections in the reference index and what their documentation says about molecular data.
| Collection | Host | Modality | Disease | Genomic pairing |
|---|---|---|---|---|
| LIDC-IDRI (opens in a new tab) | TCIA | CT | Lung nodules | Paired genomic data: not documented for this collection. |
| NSCLC Radiogenomics (opens in a new tab) | TCIA | CT, PET/CT | Non-small cell lung cancer | Paired imaging and genomic data: documented by the collection (verify per case). |
| NSCLC-Radiomics (Lung1) (opens in a new tab) | TCIA | CT | Non-small cell lung cancer | Paired genomic data: not documented for this collection. |
| TCGA-GBM (opens in a new tab) | TCIA | MRI | Glioblastoma | Genomic data available through TCGA case identifiers in the NCI GDC (documented linkage; not every case has every data type). |
| TCGA-LGG (opens in a new tab) | TCIA | MRI | Lower-grade glioma | Genomic data available through TCGA case identifiers in the NCI GDC (documented linkage; not every case has every data type). |
| TCGA-LUAD (opens in a new tab) | TCIA | CT, PET | Lung adenocarcinoma | Genomic data available through TCGA case identifiers in the NCI GDC (documented linkage; not every case has every data type). |
| TCGA-KIRC (opens in a new tab) | TCIA | CT, MRI | Clear cell renal cell carcinoma | Genomic data available through TCGA case identifiers in the NCI GDC (documented linkage; not every case has every data type). |
| TCGA-BRCA (opens in a new tab) | TCIA | MRI, mammography | Breast cancer | Genomic data available through TCGA case identifiers in the NCI GDC (documented linkage; not every case has every data type). |
| CPTAC-LUAD (opens in a new tab) | TCIA | CT, PET | Lung adenocarcinoma | Proteogenomic data available through CPTAC case identifiers (documented linkage; verify per case). |
| CPTAC-GBM (opens in a new tab) | TCIA | MRI | Glioblastoma | Proteogenomic data available through CPTAC case identifiers (documented linkage; verify per case). |
| UPENN-GBM (opens in a new tab) | TCIA | MRI | Glioblastoma | Molecular data: check the collection page; RadioGx does not assume pairing. |
| PROSTATEx (opens in a new tab) | TCIA | MRI | Prostate cancer | Paired genomic data: not documented for this collection. |
| Prostate-MRI-US-Biopsy (opens in a new tab) | TCIA | MRI, ultrasound | Prostate cancer | Paired genomic data: not documented for this collection. |
| PSMA-PET-CT-Lesions (opens in a new tab) | TCIA | PSMA PET/CT | Prostate cancer | Paired genomic data: not documented for this collection. |
| FDG-PET-CT-Lesions (opens in a new tab) | TCIA | FDG PET/CT | Lymphoma, lung cancer, melanoma | Paired genomic data: not documented for this collection. |
| CBIS-DDSM (opens in a new tab) | TCIA | Mammography | Breast lesions | Paired genomic data: not documented for this collection. |
| HNSCC (opens in a new tab) | TCIA | CT, PET/CT | Head and neck cancer | Paired genomic data: not documented for this collection. |
| RIDER Lung CT (opens in a new tab) | TCIA | CT | Lung cancer | Paired genomic data: not documented for this collection. |
Each collection has its own data usage policy and citation requirement. RadioGx never uses controlled-access data.
Radiogenomics Foundations
What it means to link an imaging phenotype to a genomic phenotype, and why public evidence is not clinical certainty.
- What radiogenomics studies
- Imaging phenotypes and genomic phenotypes
- Radiomics versus radiogenomics
- Example concepts: EGFR, KRAS, IDH, MGMT
- Public evidence versus clinical certainty
5 lessons · Students, researchers, clinicians
Imaging Biomarkers & Radiomics
What makes a measurement a biomarker, how SUV and reporting systems work, and the radiomics pipeline with its reproducibility caveats.
- What makes a measurement an imaging biomarker
- SUV and PET quantification
- Structured reporting systems
- The radiomics pipeline
- Feature families: shape, first-order, texture, higher-order
- Reproducibility caveats
- AI segmentation and deep learning: caution
7 lessons · Researchers, physicists, data scientists
Public Imaging Datasets & Genomics Resources
TCIA, NCI Imaging Data Commons, GDC and cBioPortal, how they link, and why paired imaging-genomics is never assumed.
- TCIA and the NCI Imaging Data Commons
- GDC, cBioPortal and TCGA linkage
- Paired imaging and genomics: never assume
- Controlled access, de-identification and ethics
4 lessons · Researchers, data scientists
About this tool
What is Radiogenomics workspace?
The radiogenomics workspace links imaging research questions to genes, variants, open cancer genomics frequencies, public imaging collections with documented genomic pairing, literature and trials, and labels how every link was made.
Key features
- Gene and variant lookups (MyGene, Ensembl, UniProt) with open NCI GDC frequencies
- Public imaging collections (TCIA, NCI IDC) with documented genomic pairing flagged
- Literature and trial evidence for imaging-genomic questions
- Derived links labelled as derived; no inferred imaging-genomic associations
Frequently asked questions
What is radiogenomics?
Radiogenomics studies associations between features measured on medical images and genomic or molecular features of disease, such as mutations or gene expression. Published associations are research findings that need validation, not diagnostic tests.
Does RadioGx infer imaging-genomic associations?
No. RadioGx only shows associations documented in public sources and labels each link with how it was made. It never invents or predicts an association.